Bertuzzi Stefano, Cleveland Don W
American Society for Cell Biology, Bethesda, MD, USA.
Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
Trends Cell Biol. 2015 Apr;25(4):187-9. doi: 10.1016/j.tcb.2015.02.003.
There is a general assumption that it is now time for more translational research and less basic research. Science policy leaders have sent mixed signals and the community has responded by submitting more grant applications focused on translational or applied research. Nothing could be more treacherous, because to develop innovative therapies we must more fully understand the complexities of biology, a goal requiring more, not less, basic science.
人们普遍认为,现在是时候开展更多的转化研究,减少基础研究了。科学政策领导人发出了相互矛盾的信号,科学界的回应是提交了更多侧重于转化或应用研究的资助申请。没有什么比这更危险的了,因为要开发创新疗法,我们必须更全面地了解生物学的复杂性,而这一目标需要更多而非更少的基础科学。