Strenge H, Tackmann W
Fortschr Neurol Psychiatr Grenzgeb. 1979 Aug;47(8):407-17.
The influence of thalamic lesions on the configuration of the somatosensory evoked cortical potential is studied on the basis of two own observations and of the literature. An increased latency of the initial component N1 and a reduced voltage in the beginning of the potential recorded on the side of the thalamic lesion are the most frequent findings in patients with thalamic syndromes. Most dramatic changes of the evoked response occur in cases with lesions of the VPL nucleus and with proprioceptive sensory disturbances. Considering the morphological basis of the normally configurated potential possible developmental mechanisms of the pathological evoked response are discussed.
基于两项自身观察及文献研究了丘脑病变对体感诱发电位皮层电位形态的影响。在丘脑综合征患者中，最常见的发现是丘脑病变侧记录到的电位初始成分N1潜伏期延长以及电位起始处电压降低。诱发电位的最显著变化发生在腹后外侧核（VPL）病变及本体感觉障碍的病例中。考虑到正常形态电位的形态学基础，讨论了病理性诱发电位可能的发生机制。
