Annor Francis B, Roblin Douglas W, Okosun Ike S, Goodman Michael
School of Public Health, Georgia State University, Atlanta, GA, United States.
School of Public Health, Georgia State University, Atlanta, GA, United States; Center for Health Research, Kaiser Permanente Georgia, Atlanta, GA, United States.
Diabetes Metab Syndr. 2015 Apr-Jun;9(2):85-90. doi: 10.1016/j.dsx.2015.02.003. Epub 2015 Mar 6.
To examine the association between glycosylated hemoglobin (HbA1c) and four subscales of work-related psychosocial stress at study baseline and over time.
We used survey data from a major HMO located in the Southeastern part of the US on health and healthy behaviors linked with patients' clinical, pharmacy and laboratory records for the period between 2005 and 2009. Study participants (n=537) consisted of working adults aged 25-59 years, diagnosed with diabetes mellitus (DM) but without advanced micro or macrovascular complications at the time of the survey. We estimated the baseline (2005) association between HbA1c and work-related psychosocial stress and their interactions using linear regression analysis. Using individual growth model approach, we estimated the association between HbA1c over time and work-related psychosocial stress. Each of the models controlled for socio-demographic variables, diet and physical activity factor, laboratory factor, physical examinations variables and medication use in a hierarchical fashion.
After adjusting for all study covariates, we did not find a significant association between work-related psychosocial stress and glycemic control either at baseline or over time.
Among fairly healthy middle aged working adults with DM, work-related psychosocial stress was not directly associated with glycemic control.
研究糖化血红蛋白(HbA1c)与工作相关心理社会应激的四个子量表在研究基线期及随访期间的关联。
我们使用了来自美国东南部一家大型健康维护组织(HMO)的调查数据,这些数据涉及2005年至2009年期间与患者临床、药房和实验室记录相关的健康及健康行为。研究参与者(n = 537)为年龄在25 - 59岁的在职成年人,在调查时被诊断患有糖尿病(DM),但无严重微血管或大血管并发症。我们使用线性回归分析估计HbA1c与工作相关心理社会应激及其相互作用之间的基线(2005年)关联。采用个体生长模型方法,我们估计随访期间HbA1c与工作相关心理社会应激之间的关联。每个模型均以分层方式对社会人口统计学变量、饮食和身体活动因素、实验室因素、体格检查变量及药物使用进行了控制。
在对所有研究协变量进行调整后,我们未发现工作相关心理社会应激与血糖控制在基线期或随访期间存在显著关联。
在病情相对稳定的中年在职糖尿病患者中,工作相关心理社会应激与血糖控制无直接关联。