Kahvecioğlu Dilek, Yıldız Duran, Kılıç Atilla, İnce-Alkan Banu, Erdeve Ömer, Kuloğlu Zarife, Atasay Begüm, Ensari Arzu, Yılmaz Resul, Arsan Saadet
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2014 Jul-Aug;56(4):440-3.
Tufting enteropathy is an autosomal recessive congenital enteropathy presenting with early-onset severe intractable diarrhea. It presents with watery diarrhea that develops in the first days after birth and persists despite bowel rest. Growth is impaired, and most patients require total parenteral nutrition. The histological characteristic of tufting enteropathy is the presence of epithelial tufts. We hereby present a patient who was referred to our neonatal intensive care unit because of chronic diarrhea and diagnosed with tufting enteropathy according to histological examination. To the best of our knowledge, the newborn case presented here is the first one reported from Turkey. As TE is a very rare disease, it should be considered in patients with continuing diarrhea beginning in the first days of life.
簇绒性肠病是一种常染色体隐性先天性肠病，表现为早发性严重难治性腹泻。其症状为出生后数天内出现水样腹泻，即使肠道休息也持续存在。生长发育受到影响，大多数患者需要全胃肠外营养。簇绒性肠病的组织学特征是存在上皮簇。我们在此报告一名因慢性腹泻转诊至我们新生儿重症监护病房的患者，经组织学检查诊断为簇绒性肠病。据我们所知，此处报告的新生儿病例是土耳其首例。由于簇绒性肠病是一种非常罕见的疾病，对于出生后数天开始持续腹泻的患者应予以考虑。
