人类干扰素客观生物学检测法在临床标本中的应用及正常人群调查。
Application of an objective biological assay of human interferons to clinical specimens and a survey of a normal population.
作者信息
Forti R L, Moldovan R A, Mitchell W M, Callicoat P, Schuffman S S, Davies H A, Smith D M
出版信息
J Clin Microbiol. 1985 May;21(5):689-93. doi: 10.1128/jcm.21.5.689-693.1985.
Abstract
A rapid, quantitative, and nonsubjective method of interferon assay is described, which can be readily applied to clinical specimens. Automated data acquisition and data reduction allowed a significant increase in volume per unit of time over existing methodologies. Plasma always yielded higher (usually 2:1) interferon values than did serum obtained simultaneously. Ranges of interferon levels in plasma in normal control populations are reported as well as ranges for clinical virology laboratory technicians and patients with terminal malignancies or collagen vascular diseases.
摘要
本文描述了一种快速、定量且非主观的干扰素检测方法，该方法可轻松应用于临床标本。自动化的数据采集和数据简化使得每单位时间的检测量相较于现有方法有显著增加。血浆产生的干扰素值总是高于同时采集的血清（通常为2:1）。文中报告了正常对照人群血浆中干扰素水平的范围，以及临床病毒学实验室技术人员、晚期恶性肿瘤患者或胶原血管疾病患者的干扰素水平范围。
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