Moffitt Cancer Center, Tampa, Fla.
Moffitt Cancer Center, Tampa, Fla.
Am J Med. 2015 Sep;128(9):943-9. doi: 10.1016/j.amjmed.2015.02.018. Epub 2015 Mar 27.
Intravenous contrast is commonly used in noninvasive imaging procedures such as magnetic resonance imaging and computed tomography and can evaluate blood vessels and better characterize soft-tissue lesions. Although the incidence of adverse events after administration of contrast is low, it is important that clinicians and radiologists minimize risks and respond quickly and effectively when reactions occur. We will discuss a range of adverse events to iodinated and gadolinium-based contrast agents, including allergic-like reactions, nephrotoxicity, extravasation, and nephrogenic systemic fibrosis. We will review risk stratification for patients, as well as premedication and treatment of adverse events.
静脉造影剂常用于磁共振成像和计算机断层扫描等非侵入性成像程序,可以评估血管并更好地描述软组织病变。尽管造影后发生不良反应的发生率较低,但临床医生和放射科医生在发生反应时应尽量降低风险,并迅速有效地做出反应,这一点很重要。我们将讨论碘和钆基造影剂的一系列不良反应,包括过敏样反应、肾毒性、外渗和肾源性系统性纤维化。我们将回顾患者的风险分层,以及不良反应的预防用药和治疗。