Chow Leonard, Parulekar Amit D, Hanania Nicola A
Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, Texas.
J Hosp Med. 2015 May;10(5):328-39. doi: 10.1002/jhm.2334. Epub 2015 Mar 27.
The course of chronic obstructive pulmonary disease (COPD) is often complicated by episodes of acute worsening of respiratory symptoms, which may lead to escalation of therapy and occasionally emergency department visits and hospitalization. Acute exacerbations of COPD (AECOPD) have a negative impact on quality of life and hasten the decline of lung function. They also significantly contribute to the direct and indirect healthcare costs of this disease. Severe exacerbations (those leading to hospital admission) have been associated with significant poor outcomes including an increased risk of readmissions and mortality. COPD is currently the fourth leading cause of hospital readmission in the United States. In this review, we will provide a broad overview on the etiology, assessment, management, discharge planning, and follow-up care of patients hospitalized with AECOPD.
慢性阻塞性肺疾病（COPD）的病程常因呼吸道症状急性加重发作而复杂化，这可能导致治疗升级，偶尔还会导致急诊就诊和住院。慢性阻塞性肺疾病急性加重（AECOPD）对生活质量有负面影响，并加速肺功能下降。它们还显著增加了这种疾病的直接和间接医疗费用。严重加重（导致住院）与显著不良结局相关，包括再入院风险和死亡率增加。COPD目前是美国医院再入院的第四大主要原因。在本综述中，我们将对因AECOPD住院患者的病因、评估、管理、出院计划和随访护理进行广泛概述。
