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多灶性腮腺外沃辛瘤酷似上颈部转移性鳞状细胞癌。

Multifocal extraparotid Warthin's tumours mimicking metastatic squamous cell carcinoma of the upper neck.

作者信息

Mistry S G, Gouldesbrough D, Bem C

机构信息

Department of Otolaryngology,Bradford Royal Infirmary,UK.

Department of Pathology,Bradford Royal Infirmary,UK.

出版信息

J Laryngol Otol. 2015 May;129(5):513-6. doi: 10.1017/S0022215115000638. Epub 2015 Mar 31.

DOI:10.1017/S0022215115000638
PMID:25823372
Abstract

BACKGROUND

Warthin's tumours can show features of pseudo-neoplasia. They do not usually cause problems for diagnosis and management when present within the parotid gland. However, extraparotid Warthin's tumours that are associated with pseudo-neoplasia upon cytological analysis can mimic metastatic malignant disease. The case of a patient presenting with multifocal extraparotid Warthin's tumours is described.

CASE REPORT

A 57-year-old male smoker presented with rapidly growing upper neck lumps. Fine needle aspiration cytology, magnetic resonance imaging and positron emission tomography findings were compatible with metastatic squamous cell carcinoma secondary to either an unknown primary upper aerodigestive or a parotid malignancy. The patient subsequently underwent total conservative parotidectomy and modified radical neck dissection. Final histology findings revealed multifocal benign Warthin's tumours with four extraparotid components.

CONCLUSION

Warthin's tumours may present outside the parotid gland, present with multifocal lesions and mimic metastatic disease. Frozen section examination prior to radical resection should be considered to guide management.

摘要

背景

沃辛瘤可表现出假肿瘤样特征。当位于腮腺内时,它们通常不会给诊断和治疗带来问题。然而,经细胞学分析与假肿瘤样特征相关的腮腺外沃辛瘤可酷似转移性恶性疾病。本文描述了一例出现多灶性腮腺外沃辛瘤的患者情况。

病例报告

一名57岁男性吸烟者,出现上颈部迅速增大的肿块。细针穿刺细胞学检查、磁共振成像和正电子发射断层扫描结果与继发于不明原发性上呼吸消化道或腮腺恶性肿瘤的转移性鳞状细胞癌相符。该患者随后接受了全腮腺保留切除术和改良根治性颈清扫术。最终组织学检查结果显示为多灶性良性沃辛瘤,有四个腮腺外成分。

结论

沃辛瘤可出现在腮腺外,表现为多灶性病变并酷似转移性疾病。在根治性切除术前应考虑进行冰冻切片检查以指导治疗。

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