Wu Fanglong, Weng Shengxin, Li Chunjie, Sun Jun, Li Longjiang, Gao Qinghong
Department of Oral and Maxillofacial Surgery, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China.
ORL J Otorhinolaryngol Relat Spec. 2015;77(2):70-86. doi: 10.1159/000371854. Epub 2015 Mar 20.
Submandibular gland transfer has been widely used to prevent postradiation xerostomia in head-and-neck cancers. However, there are still some controversies.
Six databases were searched, data extraction was performed and the risk of bias was assessed by 2 reviewers independently. The meta-analysis was performed using Review Manager, version 5.2.
A total of 7 trials (12 articles) and 369 participants were included.
The present clinical evidence suggests that submandibular gland transfer might be highly effective to prevent postradiation xerostomia in head-and-neck cancers without serious adverse events. However, more randomized controlled trials are still needed to confirm this conclusion.
下颌下腺转移术已广泛用于预防头颈部癌症放疗后口干症。然而，仍存在一些争议。
检索了六个数据库，进行数据提取，并由两名评价者独立评估偏倚风险。使用RevMan 5.2版进行荟萃分析。
共纳入7项试验（12篇文章）和369名参与者。
目前的临床证据表明，下颌下腺转移术可能对预防头颈部癌症放疗后口干症非常有效，且无严重不良事件。然而，仍需要更多的随机对照试验来证实这一结论。
