Jorgenson Lyric A, Newsome William T, Anderson David J, Bargmann Cornelia I, Brown Emery N, Deisseroth Karl, Donoghue John P, Hudson Kathy L, Ling Geoffrey S F, MacLeish Peter R, Marder Eve, Normann Richard A, Sanes Joshua R, Schnitzer Mark J, Sejnowski Terrence J, Tank David W, Tsien Roger Y, Ugurbil Kamil, Wingfield John C
Office of the Director, National Institutes of Health, Bethesda, MD 20892, USA
Howard Hughes Medical Institute and Stanford Neurosciences Institute, Stanford University, Stanford, CA 94305, USA
Philos Trans R Soc Lond B Biol Sci. 2015 May 19;370(1668). doi: 10.1098/rstb.2014.0164.
The evolution of the field of neuroscience has been propelled by the advent of novel technological capabilities, and the pace at which these capabilities are being developed has accelerated dramatically in the past decade. Capitalizing on this momentum, the United States launched the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to develop and apply new tools and technologies for revolutionizing our understanding of the brain. In this article, we review the scientific vision for this initiative set forth by the National Institutes of Health and discuss its implications for the future of neuroscience research. Particular emphasis is given to its potential impact on the mapping and study of neural circuits, and how this knowledge will transform our understanding of the complexity of the human brain and its diverse array of behaviours, perceptions, thoughts and emotions.
神经科学领域的发展得益于新型技术能力的出现，在过去十年中，这些能力的发展速度急剧加快。利用这一势头，美国发起了“通过推动创新神经技术进行脑研究”（BRAIN）计划，以开发和应用新工具与技术，彻底改变我们对大脑的理解。在本文中，我们回顾了美国国立卫生研究院为该计划提出的科学愿景，并讨论其对神经科学研究未来的影响。特别强调了它对神经回路图谱绘制和研究的潜在影响，以及这些知识将如何改变我们对人类大脑复杂性及其多样的行为、感知、思想和情感的理解。
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