Belcaid Mahdi, Toonen Robert J
The Hawai'i Institute of Marine Biology, P.O. Box 1346, Kane'ohe, HI, 96744, USA.
Mol Ecol. 2015 Jun;24(11):2619-40. doi: 10.1111/mec.13175. Epub 2015 May 7.
In this age of data-driven science and high-throughput biology, computational thinking is becoming an increasingly important skill for tackling both new and long-standing biological questions. However, despite its obvious importance and conspicuous integration into many areas of biology, computer science is still viewed as an obscure field that has, thus far, permeated into only a few of the biology curricula across the nation. A national survey has shown that lack of computational literacy in environmental sciences is the norm rather than the exception [Valle & Berdanier (2012) Bulletin of the Ecological Society of America, 93, 373-389]. In this article, we seek to introduce a few important concepts in computer science with the aim of providing a context-specific introduction aimed at research biologists. Our goal was to help biologists understand some of the most important mainstream computational concepts to better appreciate bioinformatics methods and trade-offs that are not obvious to the uninitiated.
在这个数据驱动的科学和高通量生物学时代，计算思维正日益成为解决新的和长期存在的生物学问题的一项重要技能。然而，尽管计算机科学具有明显的重要性且已显著融入生物学的许多领域，但它仍被视为一个晦涩难懂的领域，到目前为止，仅渗透到全国少数生物学课程中。一项全国性调查显示，环境科学领域缺乏计算素养是常态而非例外[瓦莱和伯达尼尔（2012年），《美国生态学会公报》，93，373 - 389]。在本文中，我们旨在介绍计算机科学中的一些重要概念，目的是为从事研究的生物学家提供针对特定背景的入门介绍。我们的目标是帮助生物学家理解一些最重要的主流计算概念，以便更好地理解生物信息学方法以及对于外行来说不明显的权衡取舍。
