口服高剂量地塞米松治疗ABO血型不合异基因外周血干细胞移植后纯红细胞再生障碍：一例报告
Oral High Dose Dexamethasone for Pure Red Cell Aplasia Following ABO-Mismatched Allogeneic Peripheral Blood Stem Cell Transplantation: A Case Report.
作者信息
Sharma Sanjeev Kumar, Kumar Suman, Agrawal Narendra, Mishra Pravas, Seth Tulika, Mahapatra Manoranjan
机构信息
Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Hematol Blood Transfus. 2015 Jun;31(2):317-8. doi: 10.1007/s12288-013-0276-x. Epub 2013 Jun 9.
Abstract
Management of pure red cell aplasia following major ABO-mismatched hematopoietic stem cell transplantation is a therapeutic challenge. Various therapeutic modalities have been tried with variable responses, and patient remains transfusion dependent for a long time. We report here the use of pulsed oral high dose dexamethasone for pure red cell aplasia following ABO-mismatched allogeneic transplant with complete recovery.
摘要
主要ABO血型不相合造血干细胞移植后纯红细胞再生障碍的管理是一项治疗挑战。已尝试多种治疗方式，反应各异，患者长期依赖输血。我们在此报告使用脉冲式口服高剂量地塞米松治疗ABO血型不相合异基因移植后纯红细胞再生障碍并实现完全缓解的情况。
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