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青少年可卡因滥用。成瘾潜力、行为及精神影响。

Adolescent cocaine abuse. Addictive potential, behavioral and psychiatric effects.

作者信息

Estroff T W, Schwartz R H, Hoffmann N G

机构信息

Harbor Oaks Hospital, Ft. Walton Beach, Florida.

出版信息

Clin Pediatr (Phila). 1989 Dec;28(12):550-5. doi: 10.1177/000992288902801201.

Abstract

Four hundred seventy-nine drug abusing adolescent patients enrolled in seven Straight, Inc. Adolescent Drug-Abuse Treatment Programs in five geographic regions across the United States were studied to determine the severity and patterns of cocaine abuse. Of these, 341 admitted to cocaine use and became part of this survey. Cocaine use was categorized as heavy, intermediate, or light. Areas examined were the addictive spectrum, psychosocial dysfunction, and psychiatric symptoms. Intermediate and heavy users of cocaine abused significantly less marijuana and inhalants than light cocaine abusers. Heavy and intermediate users were more likely to use cocaine intravenously and to use crack. They developed tachyphylaxis more frequently, progressed to weekly use in less than 3 months more frequently, and became preoccupied with obtaining and using cocaine significantly more frequently. They used more sedative hypnotics to calm themselves and engaged in more criminal behavior, such as stealing from parents and stores and passing bad checks. They had more arrests for possession of drugs, stole more cars, sold more drugs, and were more likely to trade sexual favors to obtain the drug. Heavy and intermediate users were significantly more psychiatrically disturbed than light users, becoming more suspicious, nervous, aggressive, and demonstrating increased symptoms of fatigue, sleeplessness, decreased appetite, and increasing cocaine dysphoria. All of these symptoms could be mistaken for psychiatric disorders. This study suggests that cocaine is as addictive in adolescents as in adults; possibly more so. It also causes psychosocial dysfunction and psychiatric symptoms. Further research into cocaine addiction among adolescents is indicated.

摘要

对在美国五个地理区域参加七个“直接行动”青少年药物滥用治疗项目的479名药物滥用青少年患者进行了研究,以确定可卡因滥用的严重程度和模式。其中,341人承认使用过可卡因并成为本次调查的一部分。可卡因使用被分为重度、中度或轻度。研究的方面包括成瘾范围、心理社会功能障碍和精神症状。与轻度可卡因滥用者相比,中度和重度可卡因使用者滥用大麻和吸入剂的情况明显较少。重度和中度使用者更有可能静脉注射可卡因并使用快克。他们更快产生快速耐受性,更频繁地在不到3个月内进展为每周使用,并且明显更频繁地沉迷于获取和使用可卡因。他们使用更多的镇静催眠药来使自己平静下来,并从事更多的犯罪行为,如从父母和商店偷窃以及开空头支票。他们因持有毒品被捕的次数更多,偷车更多,贩卖毒品更多,并且更有可能通过性交易来获取毒品。重度和中度使用者的精神障碍明显比轻度使用者更严重,变得更加多疑、紧张、好斗,并表现出疲劳、失眠、食欲减退和可卡因烦躁不安症状增加。所有这些症状都可能被误诊为精神疾病。这项研究表明,可卡因在青少年中与在成年人中一样容易成瘾;可能更容易成瘾。它还会导致心理社会功能障碍和精神症状。有必要对青少年可卡因成瘾问题进行进一步研究。

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