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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
J Exp Med. 2015 Mar 9;212(3):287-95. doi: 10.1084/jem.20142322. Epub 2015 Mar 2.
2
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Cell. 2015 Mar 12;160(6):1061-71. doi: 10.1016/j.cell.2015.01.049. Epub 2015 Feb 26.
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Anti-inflammatory signaling in microglia exacerbates Alzheimer's disease-related pathology.
Neuron. 2015 Feb 4;85(3):450-2. doi: 10.1016/j.neuron.2015.01.021.
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A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease.
J Mol Cell Biol. 2013 Oct;5(5):284-93. doi: 10.1093/jmcb/mjt028. Epub 2013 Jul 26.
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Innate immunity in the CNS: redefining the relationship between the CNS and Its environment.
Neuron. 2013 Apr 24;78(2):214-32. doi: 10.1016/j.neuron.2013.04.005.
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Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease.
Brain. 2009 Apr;132(Pt 4):1078-92. doi: 10.1093/brain/awn331. Epub 2009 Jan 17.
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