乳腺癌的正电子发射断层显像（PET）：在患者管理中的作用

PET Imaging of Breast Cancer: Role in Patient Management.

作者信息

Lebron Lizza, Greenspan Daniel, Pandit-Taskar Neeta

机构信息

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

出版信息

PET Clin. 2015 Apr;10(2):159-95. doi: 10.1016/j.cpet.2014.12.004.

DOI:10.1016/j.cpet.2014.12.004

PMID:25829085

Abstract

Breast cancer is the most common malignancy in females. Imaging plays a critical role in diagnosis, staging and surveillance, and management of disease. Fluorodeoxyglucose (FDG) PET the imaging is indicated in specific clinical setting. Sensitivity of detection depends on tumor histology and size. Whole body FDG PET can change staging and management. In recurrent disease, distant metastasis can be detected. FDG PET imaging has prognostic and predictive value. PET/MR is evolving rapidly and may play a role management, assessment of metastatic lesions, and treatment monitoring. This review discusses current PET modalities, focusing on of FDG PET imaging and novel tracers.

摘要

乳腺癌是女性最常见的恶性肿瘤。影像学在疾病的诊断、分期、监测及管理中起着关键作用。氟脱氧葡萄糖（FDG）PET成像适用于特定的临床情况。检测的敏感性取决于肿瘤的组织学类型和大小。全身FDG PET可改变分期和管理。在复发性疾病中，可以检测到远处转移。FDG PET成像具有预后和预测价值。PET/MR正在迅速发展，可能在管理、转移灶评估及治疗监测中发挥作用。本综述讨论了当前的PET模式，重点是FDG PET成像和新型示踪剂。