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18F-氟脱氧葡萄糖正电子发射断层显像/计算机断层扫描在食管癌临床管理及患者预后中的应用

PET with Fluorodeoxyglucose F 18/Computed Tomography in the Clinical Management and Patient Outcomes of Esophageal Cancer.

作者信息

Kwee Robert M, Marcus Charles, Sheikhbahaei Sara, Subramaniam Rathan M

机构信息

Department of Radiology, Maastricht University Medical Center, PO Box 5800, Maastricht 6202 AZ, The Netherlands.

Russell H Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins University, JHOC 3230, 601 N Caroline Street, Baltimore, MD 21287, USA.

出版信息

PET Clin. 2015 Apr;10(2):197-205. doi: 10.1016/j.cpet.2014.12.003. Epub 2015 Jan 29.

DOI:10.1016/j.cpet.2014.12.003
PMID:25829086
Abstract

PET with fluorodeoxyglucose F 18/computed tomography ((18)F-FDG PET/CT) has evolved into an indispensable imaging technique in the management of patients with esophageal cancer. Staging with (18)F-FDG PET/CT is strongly associated with overall survival and certain (18)F-FDG PET/CT parameters predict patient survival. Current evidence supporting the validity of the use of (18)F-FDG PET/CT in the tumor delineation process for radiation treatment planning in patients with esophageal cancer is still limited. It is useful in determining treatment response after neoadjuvant therapy and thereby has an impact on management. (18)F-FDG PET/CT plays a role in the diagnosis of recurrent disease in patients with a background of clinical suspicion.

摘要

氟脱氧葡萄糖F 18正电子发射断层显像/计算机断层扫描((18)F-FDG PET/CT)已发展成为食管癌患者管理中不可或缺的成像技术。(18)F-FDG PET/CT分期与总生存期密切相关,某些(18)F-FDG PET/CT参数可预测患者生存情况。目前支持在食管癌患者放射治疗计划的肿瘤勾画过程中使用(18)F-FDG PET/CT有效性的证据仍然有限。它有助于确定新辅助治疗后的治疗反应,从而对治疗管理产生影响。(18)F-FDG PET/CT在对有临床怀疑背景的患者复发性疾病的诊断中发挥作用。

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