为什么戈利木单抗可用于治疗银屑病关节炎、强直性脊柱炎和类风湿关节炎？
Why golimumab in the treatment of psoriatic arthritis, ankylosing spondylitis and rheumatoid arthritis?
作者信息
Rossini M, Viapiana O, Orsolini G, Fracassi E, Idolazzi L, Gatti D, Adami S, Govoni M
机构信息
Rheumatology Unit, University of Verona.
出版信息
Reumatismo. 2015 Mar 31;66(4):285-303. doi: 10.4081/reumatismo.2014.799.
PMID:25829189
Abstract
Golimumab is an anti-TNF monoclonal antibody administred subcutaneously once a month and produced with an innovative technology that minimizes immunogenicity. This paper reviews and updates the main studies on the efficacy, safety and pharmacoeconomic aspects of treatment with golimumab of psoriatic arthritis, ankylosing spondylitis and rheumatoid arthritis.
摘要
戈利木单抗是一种每月皮下注射一次的抗TNF单克隆抗体，采用创新技术生产，可将免疫原性降至最低。本文回顾并更新了关于戈利木单抗治疗银屑病关节炎、强直性脊柱炎和类风湿关节炎的疗效、安全性及药物经济学方面的主要研究。
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