一小部分慢性阻塞性肺疾病患者中存在过度的动态气道塌陷。
Excessive dynamic airway collapse in a small cohort of chronic obstructive pulmonary disease patients.
作者信息
Represas-Represas C, Leiro-Fernández V, Mallo-Alonso R, Botana-Rial M I, Tilve-Gómez A, Fernández-Villar A
机构信息
Department of Pneumology, Research Group of Respiratory and Infectious Diseases, University Hospital Complex of Vigo, Xerencia de Xestion Integrada de Vigo, Spain.
Department of Radiology, University Hospital Complex of Vigo, Xerencia de Xestion Integrada de Vigo, Spain.
出版信息
Ann Thorac Med. 2015 Apr-Jun;10(2):118-22. doi: 10.4103/1817-1737.150733.
INTRODUCTION
The prevalence of EDAC (Excessive Dynamic Airway Collapse) has not been studied specifically in patients with chronic obstructive pulmonary disease (COPD).
OBJECTIVE
The aim of this study was to investigate the prevalence of EDAC in COPD and to determine whether there are clinical factors or functional variables that could influence the degree of expiratory collapse of central airways.
METHODS
Prospective observational study of a group of patients with COPD. The degree of tracheobronchial collapse was evaluated by low-dose dynamic airway computed tomography (CT). We recorded clinical and pulmonary function tests data, quality of life and BODE index.
RESULTS
This study included 53 patients with COPD, 46 (87%) males, mean age 65 (SD, 9) years.
CONCLUSIONS
The prevalence of EDAC observed in a sample of patients with different levels of COPD severity is low. The degree of dynamic central airway collapse was not related to the patient's epidemiological or clinical features, and did not affect lung function, symptoms, capacity for effort, or quality of life.
引言
慢性阻塞性肺疾病（COPD）患者中过度动态气道塌陷（EDAC）的患病率尚未得到专门研究。
目的
本研究旨在调查COPD患者中EDAC的患病率，并确定是否存在可影响中央气道呼气塌陷程度的临床因素或功能变量。
方法
对一组COPD患者进行前瞻性观察研究。通过低剂量动态气道计算机断层扫描（CT）评估气管支气管塌陷程度。我们记录了临床和肺功能测试数据、生活质量和BODE指数。
结果
本研究纳入了53例COPD患者，其中46例（87%）为男性，平均年龄65（标准差，9）岁。
结论
在不同严重程度的COPD患者样本中观察到的EDAC患病率较低。动态中央气道塌陷程度与患者的流行病学或临床特征无关，且不影响肺功能、症状、运动能力或生活质量。
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