Mirandola Laura, Meletti Stefano, Cantalupo Gaetano
Department of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Italy ; Neurology Unit, Nuovo Ospedale Civile S. Agostino-Estense, ASL Modena, Italy.
Department of Life and Reproduction Sciences, University of Verona, Italy.
Epilepsy Behav Case Rep. 2015 Feb 24;3:20-2. doi: 10.1016/j.ebcr.2015.01.002. eCollection 2015.
We present the case of a 13-year-old child with nocturnal frontal lobe epilepsy (NFLE) related to a right cingulate gyrus cortical dysplasia, who also presented with psychogenic nonepileptic seizures (PNES) and interictal antisocial behavior. The association of drug-resistant epilepsy with behavioral disorders is well established, but the role of epilepsy surgery in these patients is still controversial, especially in children. The key finding is represented by the excellent long-term outcome on both epilepsy and behavioral dysfunction after the surgical excision of the cingulate gyrus cortical dysplasia.
我们报告了一例13岁儿童,患有与右侧扣带回皮质发育异常相关的夜间额叶癫痫(NFLE),该患儿还伴有精神性非癫痫性发作(PNES)和发作间期反社会行为。耐药性癫痫与行为障碍之间的关联已得到充分证实,但癫痫手术在这些患者中的作用仍存在争议,尤其是在儿童患者中。关键发现是扣带回皮质发育异常手术切除后,癫痫和行为功能障碍均取得了优异的长期疗效。