Frontera Jennifer, Ziai Wendy, O'Phelan Kristine, Leroux Peter D, Kirkpatrick Peter J, Diringer Michael N, Suarez Jose I
Cerebrovascular Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland Clinic Mail Code S80, Cleveland, OH, 44195, USA,
Neurocrit Care. 2015 Jun;22(3):348-59. doi: 10.1007/s12028-015-0133-x.
Regional multimodality monitoring has evolved over the last several years as a tool to understand the mechanisms of brain injury and brain function at the cellular level. Multimodality monitoring offers an important augmentation to the clinical exam and is especially useful in comatose neurocritical care patients. Cerebral microdialysis, brain tissue oxygen monitoring, and cerebral blood flow monitoring all offer insight into permutations in brain chemistry and function that occur in the context of brain injury. These tools may allow for development of individual therapeutic strategies that are mechanistically driven and goal-directed. We present a summary of the discussions that took place during the Second Neurocritical Care Research Conference regarding regional brain monitoring.
在过去几年中，区域多模态监测已发展成为一种在细胞水平上理解脑损伤机制和脑功能的工具。多模态监测为临床检查提供了重要补充，在昏迷的神经重症监护患者中尤其有用。脑微透析、脑组织氧监测和脑血流监测都有助于深入了解脑损伤情况下发生的脑化学和功能变化。这些工具可能有助于制定基于机制驱动和目标导向的个体化治疗策略。我们总结了第二届神经重症监护研究会议期间关于区域脑监测的讨论情况。
