Wagenhoffer Robert, Gruner Maren, Schymik Jan, Schachtner Lydia, Neagoe Liviu, Berg Christine, Schlichter Andreas, Manseck Andreas
Department of Urology, Klinikum Ingolstadt, Ingolstadt, Germany.
Urol Int. 2015;95(4):380-5. doi: 10.1159/000376587. Epub 2015 Mar 27.
Endoscopic extraperitoneal radical prostatectomy (EERPE) and robot-assisted laparoscopic prostatectomy (RALP) are minimally invasive surgical techniques to treat localized prostate cancer. We report the outcome and complications of these two techniques conducted by one individual surgeon.
86 patients underwent EERPE between January 2008 and June 2011, and 100 patients underwent RALP between August 2011 and October 2012. All surgeries were performed by one single surgeon.
The patients of the EERPE and RALP groups had similar clinical characteristics in PSA, prostate volume and D'Amico classification, and were significantly different in their age and BMI as well as in the number of prior surgeries. RALP surgeries were significantly slower (183 vs. 157 min) but also involved lower blood loss (147 vs. 245 ml). Pathological stages and positive surgical margins were similar in both groups. Complications were assessed by the Clavien-Dindo classification. 6 patients in the EERPE group and 3 patients of the RALP group suffered major complications (IIIb-IV).
Altogether our results indicate that the learning curve for RALP was short after experience with EERPE. We hypothesize that this is more a result of the surgical experience of the surgeon with the EERPE than on the robotic technique.
内镜下腹膜外根治性前列腺切除术(EERPE)和机器人辅助腹腔镜前列腺切除术(RALP)是治疗局限性前列腺癌的微创手术技术。我们报告由同一位外科医生实施的这两种技术的结果及并发症情况。
2008年1月至2011年6月期间,86例患者接受了EERPE手术,2011年8月至2012年10月期间,100例患者接受了RALP手术。所有手术均由同一位外科医生完成。
EERPE组和RALP组患者在前列腺特异性抗原(PSA)、前列腺体积和达米科(D'Amico)分类方面具有相似的临床特征,但在年龄、体重指数(BMI)以及既往手术次数方面存在显著差异。RALP手术时间明显更长(183分钟对157分钟),但失血量更少(147毫升对245毫升)。两组的病理分期和手术切缘阳性情况相似。并发症采用Clavien-Dindo分类法评估。EERPE组有6例患者和RALP组有3例患者发生了严重并发症(Ⅲb - Ⅳ级)。
总体而言,我们的结果表明,在有EERPE经验后,RALP的学习曲线较短。我们推测,这更多是由于外科医生在EERPE方面的手术经验,而非机器人技术本身所致。