Kreuger A L, Middelburg R A, Zwaginga J J, van der Bom J G, Kerkhoffs J-L H
Center for Clinical Transfusion Research, Sanquin Research, Leiden, The Netherlands.
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Vox Sang. 2015 Jul;109(1):91-4. doi: 10.1111/vox.12254. Epub 2015 Mar 31.
Platelets are prophylactically transfused to patients receiving myeloablative chemotherapy. The trigger can be adapted if a patient has risk factors for bleeding. We performed an international survey to quantify differences in transfusion policies. While platelet counts are most important, bleeding, fever, use of anticoagulants and invasive procedures also determine transfusion strategies. The largest variation of triggers was observed for lumbar punctures and removal of central venous catheters.
对于接受清髓性化疗的患者，预防性输注血小板。如果患者有出血风险因素，触发阈值可以调整。我们进行了一项国际调查，以量化输血政策的差异。虽然血小板计数最为重要，但出血、发热、抗凝剂的使用和侵入性操作也会决定输血策略。在腰椎穿刺和中心静脉导管拔除方面，观察到触发阈值的差异最大。
