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经口机器人手术中的决策管理:从欧洲视角看头颈部癌多学科治疗中的适应症、个体患者选择及作用

Decision management in transoral robotic surgery: Indications, individual patient selection, and role in the multidisciplinary treatment for head and neck cancer from a European perspective.

作者信息

Lörincz Balazs B, Jowett Nathan, Knecht Rainald

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery and Oncology, Head and Neck Cancer Centre of the Hubertus Wald University Cancer Centre Hamburg, University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany.

Department of Otolaryngology, Head and Neck Surgery, McGill University, Montreal, Quebec, Canada.

出版信息

Head Neck. 2016 Apr;38 Suppl 1:E2190-6. doi: 10.1002/hed.24059. Epub 2015 Jun 15.

Abstract

BACKGROUND

Transoral robotic surgery (TORS) has become an accepted first-line treatment for T1 and T2 head and neck squamous cell carcinoma (HNSCC). The growing popularity of this procedure is the result of mounting skepticism as to the survival and quality of life (QOL) benefits of primary chemoradiation over definitive surgery, the rising incidence of human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) in progressively younger patients, and the advantages of TORS over transoral laser microsurgery (TOLM) and open surgery.

METHODS

The authors use their experience and data gained from the TORS-based management of >100 patients to establish a systematic approach to the use of TORS in HNSCC.

RESULTS

This approach is constructed on a framework which goal is to select the primary treatment option that is most likely to reduce morbidity while preserving function and maintaining oncologic safety.

CONCLUSION

A consensus regarding the indications of TORS and its role in the multidisciplinary management of HNSCC is to be established. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2190-E2196, 2016.

摘要

背景

经口机器人手术(TORS)已成为T1和T2期头颈部鳞状细胞癌(HNSCC)公认的一线治疗方法。该手术日益普及的原因包括:人们越来越怀疑原发性放化疗相对于根治性手术在生存和生活质量(QOL)方面的益处;人乳头瘤病毒(HPV)阳性口咽鳞状细胞癌(OPSCC)在逐渐年轻化的患者中发病率不断上升;以及TORS相对于经口激光显微手术(TOLM)和开放手术的优势。

方法

作者利用他们在基于TORS治疗100多名患者中获得的经验和数据,建立了一种在HNSCC中使用TORS的系统方法。

结果

该方法构建在一个框架之上,其目标是选择最有可能降低发病率同时保留功能并维持肿瘤学安全性的主要治疗方案。

结论

需就TORS的适应症及其在HNSCC多学科管理中的作用达成共识。©2015威利期刊公司。《头颈》38:E2190 - E2196,2016年。

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