胰岛素对大鼠骨骼肌蛋白水解活性的影响。
Insulin effect on proteolytic activities in rat skeletal muscle.
作者信息
Röthig H J, Stiller N, Dahlmann B, Reinauer H
出版信息
Horm Metab Res. 1978 Mar;10(2):101-4. doi: 10.1055/s-0028-1093452.
PMID:25834
Abstract
Proteolytic activity has been measure in rat skeletal muscle by use of [14C]-hemoglobin as substrate. The activity of the alkaline proteinases increases during starvation and in diabetic state. In streptozotocin-diabetic animals the activity of alkaline proteases increases to 300% over a time of 21 days. Insulin treatment reverses the enhanced enzyme activity to normal level.
摘要
通过使用[14C] - 血红蛋白作为底物来测定大鼠骨骼肌中的蛋白水解活性。碱性蛋白酶的活性在饥饿期间和糖尿病状态下会增加。在链脲佐菌素诱导的糖尿病动物中，碱性蛋白酶的活性在21天内增加到300%。胰岛素治疗可将增强的酶活性恢复到正常水平。
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