基于末次月经日期的标准方法会对美国早产情况进行错误分类并高估早产率。
Standard methods based on last menstrual period dates misclassify and overestimate US preterm births.
作者信息
Ambrose C S, Caspard H, Rizzo C, Stepka E C, Keenan G
机构信息
Medical Affairs, AstraZeneca, Gaithersburg, MD, USA.
Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
出版信息
J Perinatol. 2015 Jun;35(6):411-4. doi: 10.1038/jp.2015.25. Epub 2015 Apr 2.
OBJECTIVE
To compare number of US preterm births based on obstetric versus last menstrual period (LMP) estimates and evaluate their correlations with clinical risk indicators associated with prematurity.
STUDY DESIGN
Preterm births were assessed from LMP, per standard practice, and, separately, from obstetric estimates using the 2012 Natality Public Use File. Percentages of infants with neonatal intensive care unit (NICU) admission and low birth weight (LBW) were calculated.
RESULT
More births were <37 weeks gestational age (GA) by reported LMP (11.4%) versus obstetric estimates (9.5%). Among infants preterm by LMP, but born at 37-41 weeks by obstetric estimates, there were 5.7% NICU admission and 7.7% LBW rates versus 25.2% and 35.4%, respectively, of those preterm by obstetric estimates but born 37-41 weeks by LMP assessments.
CONCLUSION
Obstetric estimates provide the most clinically relevant estimates of US preterm births. Assessments calculated from LMP alone may overestimate prematurity incidence by ~20%.
目的
比较基于产科估计与末次月经（LMP）估计的美国早产数量，并评估它们与早产相关临床风险指标的相关性。
研究设计
根据标准做法，从LMP评估早产情况，并单独使用2012年出生情况公共使用文件从产科估计中评估早产情况。计算新生儿重症监护病房（NICU）入院婴儿和低出生体重（LBW）婴儿的百分比。
结果
根据报告的LMP，孕周（GA）<37周的出生数（11.4%）多于产科估计数（9.5%）。在根据LMP为早产但根据产科估计在37 - 41周出生的婴儿中，NICU入院率为5.7%，低出生体重率为7.7%，而根据产科估计为早产但根据LMP评估在37 - 41周出生的婴儿中，这两个比率分别为25.2%和35.4%。
结论
产科估计提供了美国早产最具临床相关性的估计。仅根据LMP计算的评估可能会使早产发生率高估约20%。
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