Ishibashi Hironori, Seto Katsutoshi, Kobayashi Masatsugu, Okubo Kenichi
Department of Thoracic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Kyobu Geka. 2015 Apr;68(4):244-8.
In patients with preoperative cardiac complications such as myocardial ischemia, arrhythmia, or congestive heart failure, it is important to offer any necessary medical treatments, such as anticoagulation therapy, prior to surgery. This study investigated the perioperative results of surgical treatment for primary lung cancer in patients with cardiac complications. Data relating to 467 patients who underwent lung resection for lung cancer between April 2010 and March 2014 were collected. Perioperative factors for patients with preoperative cardiac complications and patients without preoperative cardiac complications were compared. Perioperative factors were also compared for a heparin bridging group and non-heparin bridging group in 53 anti-coagulation therapy patients.
Fifty-three (11.3%) patients had preoperative cardiac complications;the majority of these had ischemic heart disease( n=31, 58.5%), while a significant minority had atrial fibrillation( n=14, 33.3 %). Of these, 42 patients(79.2%)were receiving anti-coagulation therapy;pre-operative bridging anti-coagulation using heparin was performed in 19 patients(45.2%). There were significant differences between those patients with preoperative cardiac complications, and those without preoperative cardiac complications, in terms of sex( male;81.1% vs 65.7%, p=0.024), mean age(73.1±1.0 year vs 68.4±0.7 year, p=0.001), and duration (days) of hospitalization after surgery(10.1±2.4 vs 7.8±2.0, p=0.023). There were significant differences between patients who received pre-operative heparin bridging anticoagulation, compared with those who did not, in terms of age(70.8±1.2 year vs 76.8±0.9 year, p=0.001)and duration (days) of hospitalization after surgery(10.5±2.1 vs 7.5±1.3, p=0.005).
Fifty-three(11.3%)patients had preoperative cardiac complications. Recent changes in the demographics of surgical candidates, in terms of age, have increased the number of patients with surgical risk factors. Perioperative patient management has become more important than before.
对于术前有心脏并发症(如心肌缺血、心律失常或充血性心力衰竭)的患者,在手术前提供任何必要的医学治疗(如抗凝治疗)非常重要。本研究调查了有心脏并发症的原发性肺癌患者手术治疗的围手术期结果。收集了2010年4月至2014年3月期间467例行肺癌肺切除术患者的数据。比较了术前有心脏并发症患者和无术前心脏并发症患者的围手术期因素。还比较了53例接受抗凝治疗患者中肝素桥接组和非肝素桥接组的围手术期因素。
53例(11.3%)患者有术前心脏并发症;其中大多数患有缺血性心脏病(n = 31,58.5%),少数患有心房颤动(n = 14,33.3%)。其中,42例(79.2%)患者接受抗凝治疗;19例(45.2%)患者术前使用肝素进行桥接抗凝。术前有心脏并发症的患者与无术前心脏并发症的患者在性别(男性;81.1%对65.7%,p = 0.024)、平均年龄(73.1±1.0岁对68.4±0.7岁,p = 0.001)和术后住院天数(10.1±2.4对7.8±2.0,p = 0.023)方面存在显著差异。接受术前肝素桥接抗凝的患者与未接受的患者在年龄(70.8±1.2岁对76.8±0.9岁,p = 0.001)和术后住院天数(10.5±2.1对7.5±1.3,p = 0.005)方面存在显著差异。
53例(11.3%)患者有术前心脏并发症。手术候选者在年龄方面的人口统计学近期变化增加了具有手术风险因素的患者数量。围手术期患者管理比以前变得更加重要。