Suresh K, Nirmala K, Kuruvilla K, Vasudevan D M
Indian J Exp Biol. 1989 Jun;27(6):497-501.
Natural Killer activity assessed by 51Cr release assay from K-562 cells showed detectable activity from 5th day after tumour transplantation, reaching a peak on 12th day and thereafter showing a gradual decline in the activity. Antibody dependent cell mediated cytotoxicity estimated by 51Cr labelled sheep red blood cells anti SRBC system demonstrated a peak activity on 5th day. Cytotoxic T lymphocyte activity detected by 51Cr release of Dalton's lymphoma ascites target cells showed a peak on 10th day. Antibody complement mediated cytotoxicity revealed a similar pattern as natural killer cell activity.
通过51Cr从K - 562细胞释放试验评估的自然杀伤活性在肿瘤移植后第5天显示出可检测到的活性，在第12天达到峰值，此后活性逐渐下降。通过51Cr标记的绵羊红细胞抗SRBC系统估计的抗体依赖性细胞介导的细胞毒性在第5天显示出峰值活性。通过51Cr从道尔顿淋巴瘤腹水靶细胞释放检测到的细胞毒性T淋巴细胞活性在第10天达到峰值。抗体补体介导的细胞毒性显示出与自然杀伤细胞活性相似的模式。
