Ojha R K, Singh R, Maurya O, Agrawal J K
Indian J Ophthalmol. 1989 Apr-Jun;37(2):91-3.
Estimation of plasma cortisol by fluorometric technique desorbed by Mallingly's was carried out in 56 cases, including 38 cases of myopia (19 cases of simple myopia and 19 cases of degenerative myopia) and 18 normal individuals. Urinary 17-keto steroids/24 hours was also estimated by Zimmermann technique in 12 out of the 56 cases, which include 8 cases of myopia (4 cases of simple myopia and 4 cases of degenerative myopia) and 4 normal individuals as control. Plasma cortisol level is lower in simple and degenerative myopia than in normal subjects, but on statistical analysis the difference was not of much significance. Patients with simple myopia with positive family history showed lower value of plasma cortisol than patients with simple myopia with negative family history, the difference was also statistically insignificant (P-0.1). In degenerative myopia patients, with and without family history, there was very little difference in plasma cortisol level and statistically highly insignificant (P-0.8). Urinary 17 keto steroid/24 hour values are lower in simple and degenerative myopia than in normal subjects.
采用马林斯（Mallingly）解吸荧光法对56例患者进行血浆皮质醇测定，其中包括38例近视患者（19例单纯性近视和19例变性近视）以及18例正常个体。在这56例患者中的12例中，还采用齐默尔曼（Zimmermann）技术测定了24小时尿17 - 酮类固醇，其中包括8例近视患者（4例单纯性近视和4例变性近视）以及4例作为对照的正常个体。单纯性近视和变性近视患者的血浆皮质醇水平低于正常受试者，但经统计学分析，差异无显著意义。有阳性家族史的单纯性近视患者的血浆皮质醇值低于无阳性家族史的单纯性近视患者，差异也无统计学意义（P = 0.1）。在变性近视患者中，有无家族史的血浆皮质醇水平差异极小，统计学上极无显著意义（P = 0.8）。单纯性近视和变性近视患者的24小时尿17 - 酮类固醇值低于正常受试者。
