甲型流感感染继发横纹肌溶解症：一例病例报告及文献复习
Rhabdomyolysis secondary to influenza a infection: a case report and review of the literature.
作者信息
Fadila Mario F, Wool Kenneth J
机构信息
Department of Internal Medicine, University of Alabama at Birmingham, Health Center Montomery, USA.
出版信息
N Am J Med Sci. 2015 Mar;7(3):122-4. doi: 10.4103/1947-2714.153926.
Abstract
CONTEXT
Rhabdomyolysis is a serious clinical syndrome that results from damage to skeletal muscles. Common causes include drugs, crush injuries, seizures, heat, exertion, and infection. Viral infections, particularly Influenza A, have been recognized as a cause of rhabdomyolysis.
CASE REPORT
Our report describes a 58-year-old male who presented with viral pneumonia secondary to Influenza A virus infection. His hospital course was complicated by acute renal failure secondary to rhabdomyolysis, which was attributed to an overwhelming viremia. We discuss the differential diagnosis of rhabdomyolysis and review the literature for cases of Influenza A-related rhabdomyolysis. We also discuss the proposed mechanisms for the condition.
CONCLUSION
The scope of clinical manifestations of Influenza A infection extends beyond pulmonary syndromes. Rhabdomyolysis is being increasingly recognized as a complication of Influenza A infection with considerable morbidity and mortality.
摘要
背景
横纹肌溶解症是一种由骨骼肌损伤引起的严重临床综合征。常见病因包括药物、挤压伤、癫痫发作、高温、过度劳累和感染。病毒感染，尤其是甲型流感，已被确认为横纹肌溶解症的一个病因。
病例报告
我们的报告描述了一名58岁男性，他因甲型流感病毒感染继发病毒性肺炎。他的住院过程因横纹肌溶解症继发急性肾衰竭而复杂化，这归因于严重的病毒血症。我们讨论横纹肌溶解症的鉴别诊断，并回顾有关甲型流感相关横纹肌溶解症病例的文献。我们还讨论了该病的推测机制。
结论
甲型流感感染的临床表现范围超出肺部综合征。横纹肌溶解症越来越被认为是甲型流感感染的一种并发症，具有相当高的发病率和死亡率。
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