Hall L T
Cardiovascular Laser Center, University of California, Los Angeles.
Heart Lung. 1989 Nov;18(6):559-64.
Many possible complications are associated with cardiopulmonary bypass. They are similar to the risks accompanying most surgical procedures and include stroke, renal failure, and death. This potential for complication increases when bypass exceeds 2 hours and rises sharply when pump time is prolonged more than 3 to 4 hours. One group of serious complications is major neurologic disorders. The risk of significant cerebral dysfunction, that is, severe focal stroke or coma, is about 1%, and this risk increases with age and coexistent cardiovascular disease. This article focuses on the complication of coma and the possible role cardiopulmonary bypass plays in improving survival rates. A case study is presented illustrating the potential role of cardiopulmonary bypass in the unexpected neurologic recovery from coma.
体外循环存在许多可能的并发症。它们与大多数外科手术伴随的风险相似,包括中风、肾衰竭和死亡。当体外循环时间超过2小时,并发症的可能性会增加;当泵血时间延长超过3至4小时,风险会急剧上升。一组严重的并发症是重大神经功能障碍。严重脑功能障碍的风险,即严重局灶性中风或昏迷,约为1%,且该风险会随着年龄增长和并存的心血管疾病而增加。本文重点关注昏迷并发症以及体外循环在提高生存率方面可能发挥的作用。文中呈现了一个案例研究,阐明了体外循环在昏迷后意外神经功能恢复中可能发挥的作用。