Faculty of Medicine, Chulalongkorn University.
Asian Pac J Allergy Immunol. 2015 Mar;33(1):65-8. doi: 10.12932/AP0416.33.1.2015.
Several fruits have been reported to crossreact with latex antigen in latex allergy patients but little is known regarding tropical fruits in particular. Here we report the case of a 34-year old nurse who developed anaphylaxis following the ingestion of dried jackfruit (Artocarpus heterophyllus). The patient had a history of chronic eczema on both hands resulting from a regular wear of latex gloves. She and her family also had a history of atopy (allergic rhinitis and/or atopic dermatitis). The results of skin prick tests were positive for jackfruit, latex glove, kiwi and papaya, but the test was negative for banana. While we are reporting the first case of jackfruit anaphylaxis, further research needs to be conducted to identify the mechanisms underlying it. In particular, in-vitro studies need to be designed to understand if the anaphylaxis we describe is due to a cross reactivity between latex and jackfruit or a coincidence of allergy to these 2 antigens.
几种水果已被报道在乳胶过敏患者中与乳胶抗原发生交叉反应,但对于热带水果知之甚少。在这里,我们报告了一例 34 岁护士在食用干菠萝蜜(Artocarpus heterophyllus)后发生过敏反应的病例。该患者双手患有慢性湿疹,由于经常佩戴乳胶手套所致。她和她的家人也有特应性(过敏性鼻炎和/或特应性皮炎)病史。皮肤点刺试验结果对菠萝蜜、乳胶手套、奇异果和木瓜呈阳性,但香蕉试验为阴性。虽然我们报告了首例菠萝蜜过敏反应的病例,但仍需要进一步研究以确定其发病机制。特别是需要设计体外研究来了解我们所描述的过敏反应是由于乳胶和菠萝蜜之间的交叉反应,还是对这两种抗原过敏的巧合。