Isola Stefania, Ricciardi Luisa, Saitta Salvatore, Fedele Roberta, Mazzeo Letteria, Fogliani Olga, Gangemi Sebastiano, Purello-D'Ambrosio Francesco
School and Division of Allergy and Clinical Immunology, University of Messina, Italy.
Allergy Asthma Proc. 2003 May-Jun;24(3):193-7.
Since the first case reported in 1927, latex allergy has attracted the attention of allergists including its capacity to cross-react with fruits. To evaluate the frequency of sensitivity to some fruit allergens shown to cross-react with latex, we evaluated 82 patients (43 men and 39 women, aged between 18 and 45 years) with latex allergy. All patients underwent skin tests with various fruit extracts that potentially cross-react with latex. Only patients with negative prick tests successively underwent prick-by-prick tests with fresh fruits. Thirty-nine of 82 patients (47.5%) were found to have positive skin tests. Prick tests with fruit extracts were positive in 28 patients (kiwi, 21 patients; banana, 17 patients; avocado, 8 patients; and papaya, 3 patients), and the prick-by-prick test had positive results in 11 patients (kiwi, 7 patients; banana, 4 patients; and avocado, 3 patients). In our experience patients with latex allergy are at a high risk of sensitization to some fruits and they often develop allergic reactions, even severe ones, after eating them; for this reason fruit sensitization should be taken into consideration when investigating patients allergic to natural rubber latex.
自1927年首例病例报告以来，乳胶过敏已引起过敏症专科医生的关注，包括其与水果发生交叉反应的能力。为了评估对某些已证明与乳胶发生交叉反应的水果过敏原敏感的频率，我们对82例乳胶过敏患者（43名男性和39名女性，年龄在18至45岁之间）进行了评估。所有患者均接受了与乳胶可能发生交叉反应的各种水果提取物的皮肤试验。只有点刺试验阴性的患者依次接受了新鲜水果的逐点刺试验。82例患者中有39例（47.5%）皮肤试验呈阳性。水果提取物点刺试验阳性的有28例（猕猴桃，21例；香蕉，17例；鳄梨，8例；木瓜，3例），逐点刺试验阳性的有11例（猕猴桃，7例；香蕉，4例；鳄梨，3例）。根据我们的经验，乳胶过敏患者对某些水果致敏的风险很高，食用后常发生过敏反应，甚至严重反应；因此，在调查天然橡胶乳胶过敏患者时应考虑水果致敏情况。
