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围产期感染艾滋病毒的青少年和青年对麻疹的易感性。

Susceptibility to Measles Among Perinatally HIV-Infected Adolescents and Young Adults.

作者信息

Morris Lee E, Posada Roberto, Hickman Carole J, Latner Donald R, Singh Tricia A, Rautenberg Alyssa, Jao Jennifer, Bellini William J, Sperling Rhoda

机构信息

Division of Pediatric Infectious Disease, Mount Sinai School of Medicine, New York, New York.

Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

出版信息

J Pediatric Infect Dis Soc. 2015 Mar;4(1):63-6. doi: 10.1093/jpids/pit054. Epub 2013 Sep 24.

DOI:10.1093/jpids/pit054
PMID:25844166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4381743/
Abstract

Among our cohort of adolescents and young adults with perinatally acquired human immunodeficiency virus, few (17.6%) had measles protective antibodies by plaque reduction neutralization (PRN). Agreement was demonstrated between the commercial enzyme immunoassay and the PRN assay (K = 0.59 [95% confidence interval: 0.23-0.95]). Further studies are needed to understand the determinants of immunity in this population.

摘要

在我们患有围产期获得性人类免疫缺陷病毒的青少年和青年队列中，通过空斑减少中和试验（PRN）检测，只有少数人（17.6%）具有麻疹保护性抗体。商业酶免疫测定法和PRN测定法之间显示出一致性（K = 0.59 [95%置信区间：0.23 - 0.95]）。需要进一步研究以了解该人群免疫的决定因素。

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