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消化性溃疡出血的内镜治疗

Endoscopic management of peptic ulcer bleeding.

作者信息

Kim Joon Sung, Park Sung Min, Kim Byung-Wook

机构信息

Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.

出版信息

Clin Endosc. 2015 Mar;48(2):106-11. doi: 10.5946/ce.2015.48.2.106. Epub 2015 Mar 27.

DOI:10.5946/ce.2015.48.2.106
PMID:25844337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4381136/
Abstract

Acute upper gastrointestinal bleeding is a common medical emergency around the world and the major cause is peptic ulcer bleeding. Endoscopic treatment is fundamental for the management of peptic ulcer bleeding. Despite recent advances in endoscopic treatment, mortality from peptic ulcer bleeding has still remained high. This is because the disease often occurs in elderly patients with frequent comorbidities and are taking ulcerogenic medications. Therefore, the management of peptic ulcer bleeding is still a challenge for clinicians. This article reviews the various endoscopic methods available for management of peptic ulcer bleeding and the techniques in using these methods.

摘要

急性上消化道出血是全球常见的医疗急症,主要病因是消化性溃疡出血。内镜治疗是消化性溃疡出血管理的基础。尽管内镜治疗近年来取得了进展,但消化性溃疡出血的死亡率仍然很高。这是因为该疾病常发生于伴有多种合并症且正在服用致溃疡药物的老年患者中。因此,消化性溃疡出血的管理对临床医生来说仍然是一项挑战。本文综述了可用于管理消化性溃疡出血的各种内镜方法以及使用这些方法的技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/c1d95cccaa28/ce-48-106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/06e81452f81d/ce-48-106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/4f04a637ef54/ce-48-106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/c1d95cccaa28/ce-48-106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/06e81452f81d/ce-48-106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/4f04a637ef54/ce-48-106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/4381136/c1d95cccaa28/ce-48-106-g003.jpg

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本文引用的文献

1
Endoscopy for nonvariceal upper gastrointestinal bleeding.非静脉曲张性上消化道出血的内镜检查
Clin Endosc. 2014 Jul;47(4):315-9. doi: 10.5946/ce.2014.47.4.315. Epub 2014 Jul 28.
2
Reassessment of the predictive value of the Forrest classification for peptic ulcer rebleeding and mortality: can classification be simplified?重新评估 Forrest 分级对消化性溃疡再出血和死亡率的预测价值:能否简化分类?
Endoscopy. 2014 Jan;46(1):46-52. doi: 10.1055/s-0033-1344884. Epub 2013 Nov 11.
3
Challenges in the management of acute peptic ulcer bleeding.
Dig Dis Sci. 2021 Nov;66(11):3698-3714. doi: 10.1007/s10620-020-06728-y. Epub 2021 Jan 6.
4
Correlation between the Glasgow-Blatchford score, shock index, and Forrest classification in patients with peptic ulcer bleeding.消化性溃疡出血患者的 Glasgow-Blatchford 评分、休克指数与 Forrest 分级的相关性。
Turk J Med Sci. 2020 Jun 23;50(4):706-712. doi: 10.3906/sag-1906-154.
5
Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding.酒精滥用增加非静脉曲张性上消化道出血患者的再出血风险和死亡率。
Dig Dis Sci. 2015 Dec;60(12):3707-15. doi: 10.1007/s10620-015-3806-6. Epub 2015 Jul 16.
急性消化性溃疡出血的处理难点。
Lancet. 2013 Jun 8;381(9882):2033-43. doi: 10.1016/S0140-6736(13)60596-6.
4
Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009.2001 年至 2009 年美国胃肠道并发症住院和死亡的发病趋势。
Am J Gastroenterol. 2012 Aug;107(8):1190-5; quiz 1196. doi: 10.1038/ajg.2012.168. Epub 2012 Jun 12.
5
A comparison of surgery versus transcatheter angiographic embolization in the treatment of nonvariceal upper gastrointestinal bleeding uncontrolled by endoscopy.比较手术与经导管血管造影栓塞治疗内镜治疗未能控制的非静脉曲张性上消化道出血。
Eur J Gastroenterol Hepatol. 2012 Aug;24(8):929-38. doi: 10.1097/MEG.0b013e32835463bc.
6
Management of patients with ulcer bleeding.溃疡出血患者的处理。
Am J Gastroenterol. 2012 Mar;107(3):345-60; quiz 361. doi: 10.1038/ajg.2011.480. Epub 2012 Feb 7.
7
Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality.复杂型消化性溃疡病的流行病学:发病率、复发率、危险因素和死亡率的系统评价。
Digestion. 2011;84(2):102-13. doi: 10.1159/000323958. Epub 2011 Apr 14.
8
Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit.英国急性上消化道出血:2007 年英国审核中的患者特征、诊断和结局。
Gut. 2011 Oct;60(10):1327-35. doi: 10.1136/gut.2010.228437. Epub 2011 Apr 13.
9
A comparison of angiographic embolization with surgery after failed endoscopic hemostasis to bleeding peptic ulcers.对比内镜止血失败后的出血性消化性溃疡患者采用血管造影栓塞与手术治疗的效果。
Gastrointest Endosc. 2011 May;73(5):900-8. doi: 10.1016/j.gie.2010.11.024. Epub 2011 Feb 2.
10
Prokinetics in acute upper GI bleeding: a meta-analysis.促动力剂治疗急性上消化道出血的荟萃分析。
Gastrointest Endosc. 2010 Dec;72(6):1138-45. doi: 10.1016/j.gie.2010.08.011.