Umbert I J, Su W P
Department of Dermatology, Mayo Clinic and Rochester, MN 55905.
J Am Acad Dermatol. 1989 Dec;21(6):1232-4. doi: 10.1016/s0190-9622(89)70336-4.
We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case the hyphae could be observed in the epidermis. To our knowledge, this is the only reported case of primary cutaneous mucormycosis with hyphae detectable in the epidermis.
我们报告了两例免疫功能低下患者的原发性皮肤毛霉病病例。尽管其临床表现为非特异性坏死性溃疡，但组织病理学特征具有诊断意义。在这两例病例中，均在真皮和皮下组织中发现了粗大、分支、无隔膜的菌丝。在其中一例病例中，表皮中也可观察到菌丝。据我们所知，这是唯一一例报告的原发性皮肤毛霉病病例，其表皮中可检测到菌丝。
