[一次性给予苯巴比妥和四氯化碳对大鼠肝脏共突变活性的影响]
[The effect of a one-time administration of phenobarbital and carbon tetrachloride on comuton activity in the rat liver].
作者信息
Elbakidze G M, Chelidze M A, Elbakidze I M
出版信息
Izv Akad Nauk SSSR Biol. 1989 Sep-Oct(5):666-73.
PMID:2584531
Abstract
Infusion of phenobarbital and CCl4 was found to induce comuton control of mitochondrial respiration in a liver of starved rats. Comuton regulation of liver mitochondria respiration can be activated either by increase in liver activity or by damage caused by CCl4. The comuton regulation is directly induced by disturbance of energetic homeostasis of liver cells.
摘要
已发现，对饥饿大鼠的肝脏注入苯巴比妥和四氯化碳可诱导线粒体呼吸的共同控制。肝脏线粒体呼吸的共同控制可通过肝脏活性增加或四氯化碳造成的损伤来激活。共同控制是由肝细胞能量稳态的紊乱直接诱导的。
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