Chan G C W, Yap D Y H, Kwan L P Y, Chan J F W, Iu L P, Wong I Y, Tang S C W
Department of Medicine, Queen Mary Hospital, Hong Kong, China.
Division of Nephrology, Department of Medicine, The University of Hong Kong, Hong Kong, China.
Transpl Infect Dis. 2015 Jun;17(3):396-9. doi: 10.1111/tid.12385. Epub 2015 May 19.
Renal transplant recipients (RTRs) are subject to a variety of opportunistic infections. We present a rare case of varicella zoster virus-derived progressive outer retinal necrosis in an RTR, who presented with painless visual blurring. This clinical entity heralds an extremely poor visual prognosis and is an important condition to consider in any immunocompromised host. Early diagnosis by aqueous fluid sampling and immediate institution of combined systemic and intravitreal antiviral therapy was successful in this individual.