Smith Saxon D, Lee Andrew, Blaszczynski Alex, Fischer Gayle
Dermatology and Skin Cancer Centre, Gosford, New South Wales, Australia.
Department of Dermatology, Royal North Shore Hospital, Sydney, New South Wales, Australia.
Australas J Dermatol. 2016 Aug;57(3):199-204. doi: 10.1111/ajd.12339. Epub 2015 Apr 5.
BACKGROUND/OBJECTIVES: Topical corticosteroids (TCS) are the standard of care in paediatric atopic dermatitis (pAD). Parents commonly cite TCS phobia as a major impediment to treatment adherence. Misinformation on TCS side-effects can impact on perceptions of TCS safety. We aimed to assess pharmacists' beliefs and information on the safety of TCS in pAD treatment and determine whether their beliefs could be modified.
Australian pharmacists attending a continuing professional development conference were assessed before and after an evidence-based lecture on the use of TCS in pAD. Responses were recorded in real time on electronic keypads.
The mean response rate was 86% of the 292 surveyed. Of responders, 64% recognised that treatment non-adherence was a major reason for treatment failure in pAD. The post-education session assessment demonstrated a major attitude shift compared to the pre-education assessment. After education, pharmacists would instruct parents/patients to apply TCS until the eczema is clear (27 vs 92% pre and post-education, P < 0.0001). The proportion that would instruct patients to use TCS sparingly dropped from 54 to 8% (P < 0.0001). The belief that cutaneous atrophy was the commonest side-effect dropped from 46 to 7% (P < 0.0001). The belief that side-effects from TCS would occur, even if used appropriately, dropped from 56 to 11% post-education (P < 0.0001).
The significant knowledge gaps about the use and safety of TCS in pAD in Australian pharmacists and their advice to patients potentially contributes to poor treatment concordance. These attitudes appear modifiable through targeted, evidence-based education delivered by a dermatologist.
背景/目的:外用糖皮质激素(TCS)是儿童特应性皮炎(pAD)的标准治疗药物。家长普遍表示,对TCS的恐惧是影响治疗依从性的主要障碍。关于TCS副作用的错误信息会影响对TCS安全性的认知。我们旨在评估药剂师对TCS在pAD治疗中安全性的看法和信息,并确定他们的看法是否可以改变。
参加继续职业发展会议的澳大利亚药剂师在一场关于TCS在pAD中应用的循证讲座前后接受评估。通过电子键盘实时记录回答。
在292名接受调查者中,平均回复率为86%。在回复者中,64%认识到治疗不依从是pAD治疗失败的主要原因。与教育前评估相比,教育后评估显示出主要态度转变。教育后,药剂师会指导家长/患者持续使用TCS直至湿疹消退(教育前为27%,教育后为92%,P<0.0001)。建议患者谨慎使用TCS的比例从54%降至8%(P<0.0001)。认为皮肤萎缩是最常见副作用的比例从46%降至7%(P<0.0001)。认为即使正确使用TCS也会出现副作用的比例在教育后从56%降至11%(P<0.0001)。
澳大利亚药剂师在TCS在pAD中的使用和安全性方面存在重大知识差距,他们给患者的建议可能导致治疗依从性差。通过皮肤科医生提供的有针对性的循证教育,这些态度似乎是可以改变的。