Ashida H, Utsunomiya J, Kotoura Y, Ishikawa Y, Nishioka A, Takagi K, Fukuda M
Second Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
J Clin Gastroenterol. 1989 Dec;11(6):658-62. doi: 10.1097/00004836-198912000-00012.
From December 1973 to December 1987, we performed a distal splenorenal shunt (DSRS) in 112 cases of portal hypertension, including 107 with postnecrotic liver cirrhosis and 5 with idiopathic portal hypertension (IPH). They comprised about 50% of our surgical cases with esophageal varices. In 1981, we modified our operative procedure towards a more extended splenopancreatic disconnection (SPD) in order to prevent the "stealing" of the shunt through the pancreatic vein. In one group of 69 patients who underwent DSRS alone, the operative mortality was 2.9%; postoperative encephalopathy was seen in 17.4%, late hepatic failure in 40.6%, and recurrence of varices in 4.3%. In the other group, 43 patients who underwent DSRS with SPD, there were no operative deaths, no encephalopathy (better than DSRS alone at p less than 0.05), and late hepatic failure was seen in only 9.3% (better than DSRS alone at p less than 0.025), while the recurrence rate of 7% was the only statistical increase. These data show that DSRS + SPD can improve chances of survival.
1973年12月至1987年12月,我们对112例门静脉高压症患者施行了远端脾肾分流术(DSRS),其中107例为坏死后肝硬化,5例为特发性门静脉高压症(IPH)。这些患者约占我们食管静脉曲张手术病例的50%。1981年,我们改进了手术方法,采用更广泛的脾胰断流术(SPD),以防止分流通过胰静脉“窃血”。在仅接受DSRS的69例患者中,手术死亡率为2.9%;术后脑病发生率为17.4%,晚期肝衰竭发生率为40.6%,静脉曲张复发率为4.3%。在另一组43例接受DSRS加SPD的患者中,无手术死亡,无脑病发生(优于单纯DSRS,P<0.05),晚期肝衰竭发生率仅为9.3%(优于单纯DSRS,P<0.025),而7%的复发率是唯一有统计学意义的增加。这些数据表明,DSRS+SPD可提高生存率。