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腭裂手术的患病率、人口统计学特征及并发症

Prevalence, demographics, and complications of cleft palate surgery.

作者信息

Mahboubi Hossein, Truong Adam, Pham Nguyen S

机构信息

Department of Otolaryngology - Head and Neck Surgery, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868, USA.

Department of Otolaryngology - Head and Neck Surgery, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868, USA; Division of Pediatric Otolaryngology, CHOC Children's Hospital, 1201 W. La Veta Ave., Orange, CA 92868, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2015 Jun;79(6):803-807. doi: 10.1016/j.ijporl.2015.02.032. Epub 2015 Mar 6.

Abstract

INTRODUCTION

Current published data on the demographics of cleft lip and palate is sparse and differs intranationally in reported incidence, demographics, and complication rates, making accurate local data both valuable and useful. We investigate the prevalence, demographics, and complications of cleft palate correction surgery in the inpatient setting over a 15-year period.

METHODS

A retrospective review of The California Hospital Discharge Data sets of all pediatric patients who underwent cleft palate repair or cleft palate revision from 1997 to 2011. Children's hospitals (CHs) were analyzed as a separate group. For each record, age, gender, ethnicity, length of stay, total charges, principal payer, complications, and disposition were analyzed.

RESULTS

10,450 correction surgeries were performed during 1997-2011. This was an annual case-volume of 697 and annual population-adjusted rate of 2.0, neither of which changed over time (p=0.9 and 0.06, respectively). Of all surgeries, 21.5% were revisions, 48.3% were performed in CHs, 56.2% were performed on males, and 65.5% were performed on Caucasians. The median length of stay was 1 day, which did not change over time (p=1.0). The median total charges increased from $9.074 to $35,643 over the studied period (p<0.001). Admission to CHs was associated with shorter stay (1-3 days vs. 1-4 days) and higher total charges ($15,560 vs. $13,242; both p<0.001). Complications occurred in 393 (3.8%) of the surgeries. This percentage did not change over time (p=0.2). The most common complication was fistula/abscess/infection, which occurred in 159 cases (1.5%). Respiratory complications requiring ventilation occurred 66 cases (0.6%). Complications were more common in CHs (4.8% vs. 2.8%; p<0.001). Mortality rate was <0.1%.

CONCLUSIONS

Our study constitutes the entire surgical cohort within a state, allowing for an accurate representation of the true perioperative complication rate of these procedures. The prevalence, demographics, and outcomes of the cleft palate correction surgery have remained unchanged during 1997-2011. Collectively, our data suggest that primary and secondary palatoplasty present low perioperative risk.

摘要

引言

目前已发表的有关唇腭裂人口统计学的数据较为稀少,且在全国范围内报告的发病率、人口统计学特征及并发症发生率存在差异,因此准确的本地数据兼具价值和实用性。我们调查了15年间住院环境下腭裂修复手术的患病率、人口统计学特征及并发症情况。

方法

对1997年至2011年期间在加利福尼亚州所有接受腭裂修复或腭裂修复术修订的儿科患者的医院出院数据集进行回顾性分析。儿童医院单独作为一组进行分析。对每条记录的年龄、性别、种族、住院时间、总费用、主要支付方、并发症及出院情况进行分析。

结果

1997年至2011年期间共进行了10450例修复手术。年病例数为697例,年人口调整率为2.0,两者均未随时间变化(p分别为0.9和0.06)。在所有手术中,21.5%为修订手术,48.3%在儿童医院进行,56.2%的手术对象为男性,65.5%的手术对象为白种人。中位住院时间为1天,未随时间变化(p = 1.0)。在研究期间,中位总费用从9074美元增加到35643美元(p < 0.001)。入住儿童医院与住院时间较短(1 - 3天对1 - 4天)及总费用较高相关(15560美元对13242美元;两者p < 0.001)。393例(3.8%)手术出现并发症。该百分比未随时间变化(p = 0.2)。最常见的并发症是瘘管/脓肿/感染,共159例(1.5%)。需要通气的呼吸并发症有66例(0.6%)。并发症在儿童医院更为常见(4.8%对2.8%;p < 0.001)。死亡率<0.1%。

结论

我们的研究涵盖了一个州内的整个手术队列,能够准确反映这些手术的真实围手术期并发症发生率。1997年至2011年期间,腭裂修复手术的患病率、人口统计学特征及结果保持不变。总体而言,我们的数据表明一期和二期腭裂修复术的围手术期风险较低。

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