Ruhdorfer Anja S, Azaryan Mihran, Kraus Joerg, Grinzinger Susanne, Hitzl Wolfgang, Ebmer Johannes, Dellon A Lee, Hölzl Bertram
Department of Internal Medicine, Landesklinik St. Veit im Pongau, SALK, Paracelsus Medical University, Salzburg, Austria.
Department of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria.
Microsurgery. 2015 Oct;35(7):512-7. doi: 10.1002/micr.22409. Epub 2015 Apr 3.
Microneurolysis of entrapped peripheral nerve has the best chance of success when compression has not created significant axonal loss. The purpose of this study is to learn the best way to identify potential surgical candidates at the earliest time for intervention, by examining patients in a clinical setting using objective, electrodiagnostic nerve conduction studies (NCS), and subjective touch threshold studies, Semmes-Weinstein monofilaments (SWM) and Pressure-Specified Sensory Device™ (PSSD). Fifty-five patients with diabetic polyneuropathy over the age of 30 years were included. Neuropathy symptom score was the gold standard for statistical calculation, with a prevalence of 70%. In the symptomatic population, prevalence was 64% for NCS (n = 25), 59% for SWM (n = 43), and 88% for PSSD (n = 51). In the asymptomatic population, prevalence was 70% for NCS, 27% for SWM, and 92% for PSSD. It is concluded that the PSSD is the most sensitive device of those tested for identifying peripheral neuropathy in an at risk population of patients.
当压迫尚未造成显著轴突损失时，对受压周围神经进行微神经松解术成功的机会最大。本研究的目的是通过在临床环境中使用客观的电诊断神经传导研究（NCS）以及主观触觉阈值研究、Semmes-Weinstein单丝（SWM）和压力特定感觉装置（PSSD）对患者进行检查，找出在最早时间识别潜在手术候选者以进行干预的最佳方法。纳入了55名年龄超过30岁的糖尿病性多发性神经病患者。神经病变症状评分是统计计算的金标准，患病率为70%。在有症状人群中，NCS的患病率为64%（n = 25），SWM为59%（n = 43），PSSD为88%（n = 51）。在无症状人群中，NCS的患病率为70%，SWM为27%，PSSD为92%。得出的结论是，在对有风险的患者群体进行外周神经病变识别测试的设备中，PSSD是最敏感的。
