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体液中电离辐射对人类免疫缺陷病毒(HIV)的灭活作用及血清学证据。

Inactivation of human immunodeficiency virus (HIV) by ionizing radiation in body fluids and serological evidence.

作者信息

Bigbee P D, Sarin P S, Humphreys J C, Eubanks W G, Sun D, Hocken D G, Thornton A, Adams D E, Simic M G

机构信息

Forensic Science Research and Training Center, FBI Academy, Quantico, VA.

出版信息

J Forensic Sci. 1989 Nov;34(6):1303-10.

PMID:2584940
Abstract

A method to use ionizing radiation to inactivate HIV (Human Immunodeficiency Virus) in human body fluids was studied in an effort to reduce the risk of accidental infection to forensic science laboratory workers. Experiments conducted indicate that an X-ray absorbed dose of 25 krad was required to completely inactivate HIV. This does not alter forensically important constituents such as enzymes and proteins in body fluids. This method of inactivation of HIV cannot be used on body fluids which will be subjected to deoxyribonucleic acid (DNA) typing.

摘要

为降低法医科学实验室工作人员意外感染的风险,研究了一种利用电离辐射使人体体液中的艾滋病毒(人类免疫缺陷病毒)失活的方法。进行的实验表明,需要25千拉德的X射线吸收剂量才能使艾滋病毒完全失活。这不会改变体液中酶和蛋白质等对法医鉴定重要的成分。这种使艾滋病毒失活的方法不能用于将进行脱氧核糖核酸(DNA)分型的体液。

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J Forensic Sci. 1989 Nov;34(6):1303-10.
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