Hedman Erik, Lekander Mats, Ljótsson Brjánn, Lindefors Nils, Rück Christian, Andersson Gerhard, Andersson Erik
Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden; Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden.
Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden; Stockholm University, Stress Research Institute, Stockholm, Sweden.
PLoS One. 2015 Apr 7;10(4):e0123412. doi: 10.1371/journal.pone.0123412. eCollection 2015.
Health anxiety can be viewed as a dimensional phenomenon where severe health anxiety in form of DSM-IV hypochondriasis represents a cut-off where the health anxiety becomes clinically significant. Three of the most reliable and used self-report measures of health anxiety are the Health Anxiety Inventory (HAI), the Illness Attitude Scales (IAS) and the Whiteley Index (WI). Identifying the optimal cut-offs for classification of presence of a diagnosis of severe health anxiety on these measures has several advantages in clinical and research settings. The aim of this study was therefore to investigate the HAI, IAS and WI as proximal diagnostic instruments for severe health anxiety defined as DSM-IV hypochondriasis.
We investigated sensitivity, specificity and predictive value on the HAI, IAS and WI using a total of 347 adult participants of whom 158 had a diagnosis of severe health anxiety, 97 had obsessive-compulsive disorder and 92 were healthy non-clinical controls. Diagnostic assessments were conducted using the Anxiety Disorder Interview Schedule.
Optimal cut-offs for identifying a diagnosis of severe health anxiety was 67 on the HAI, 47 on the IAS, and 5 on the WI. Sensitivity and specificity were high, ranging from 92.6 to 99.4%. Positive and negative predictive values ranged from 91.6 to 99.4% using unadjusted prevalence rates.
The HAI, IAS and WI have very good properties as diagnostic indicators of severe health anxiety and can be used as cost-efficient proximal estimates of the diagnosis.
健康焦虑可被视为一种维度现象,其中以DSM-IV疑病症形式出现的严重健康焦虑代表了一个临界点,此时健康焦虑在临床上具有显著意义。健康焦虑最可靠且常用的三种自我报告测量工具是健康焦虑量表(HAI)、疾病态度量表(IAS)和惠特利指数(WI)。确定这些测量工具上严重健康焦虑诊断存在的最佳临界点在临床和研究环境中有诸多优势。因此,本研究的目的是调查HAI、IAS和WI作为定义为DSM-IV疑病症的严重健康焦虑的近端诊断工具。
我们对HAI、IAS和WI的敏感性、特异性和预测价值进行了调查,共纳入347名成年参与者,其中158人被诊断为严重健康焦虑,97人患有强迫症,92人为健康非临床对照。使用焦虑障碍访谈量表进行诊断评估。
识别严重健康焦虑诊断的最佳临界点在HAI上为67,在IAS上为47,在WI上为5。敏感性和特异性较高,范围从92.6%至99.4%。使用未调整的患病率时,阳性和阴性预测值范围从91.6%至99.4%。
HAI、IAS和WI作为严重健康焦虑的诊断指标具有非常好的特性,可作为该诊断的经济高效的近端评估工具。