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尿道断裂伤的初次内镜下复位——一把双刃剑?

Primary Endoscopic Realignment of Urethral Disruption Injuries--A Double-Edged Sword?

作者信息

Johnsen Niels V, Dmochowski Roger R, Mock Stephen, Reynolds W Stuart, Milam Douglas F, Kaufman Melissa R

机构信息

Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.

Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.

出版信息

J Urol. 2015 Oct;194(4):1022-6. doi: 10.1016/j.juro.2015.03.112. Epub 2015 Apr 4.

Abstract

PURPOSE

Controversy remains regarding initial management of traumatic urethral disruption injuries. We evaluated the outcomes of primary endoscopic realignment vs suprapubic tube placement in this patient population.

MATERIALS AND METHODS

We reviewed our urological trauma database for patients with blunt trauma related posterior urethral injuries from 2000 to 2014. Patients underwent primary endoscopic realignment or suprapubic tube placement alone. The primary outcome was the success of primary realignment, defined as no further need for urological intervention. Secondary outcomes were the need for endoscopic interventions and/or urethroplasty, time to urethroplasty, urethroplasty success and long-term functional outcomes.

RESULTS

A total of 27 patients underwent primary realignment and 14 underwent suprapubic tube placement. Mean followup was 40 months (median 24, range 1 to 152). Realignment was successful in 10 patients (37%) at a mean followup of 67.3 weeks (median 27.3, range 4 to 284). In the 17 cases (63%) that failed mean time to failure was 9.7 weeks (median 8.5, range 1 to 26). Seven patients (26%) treated with realignment and 11 (79%) with a suprapubic tube proceeded to urethroplasty. Mean ± SD time to urethroplasty was significantly shorter in the suprapubic tube group (14.6 ± 7.6 vs 5.8 ± 1.6 months, p = 0.003). There was no difference in operative time, complications, success or functional outcomes.

CONCLUSIONS

Management of traumatic urethral disruption injuries by primary endoscopic realignment serves as definitive therapy in more than a third of treated patients. It prevents the need for formal urethroplasty in more than half of failed cases.

摘要

目的

创伤性尿道断裂伤的初始治疗仍存在争议。我们评估了该患者群体中一期内镜下尿道会师术与耻骨上膀胱造瘘管置入术的治疗效果。

材料与方法

我们回顾了2000年至2014年因钝性创伤导致后尿道损伤患者的泌尿外科创伤数据库。患者分别接受了一期内镜下尿道会师术或单纯耻骨上膀胱造瘘管置入术。主要结局是一期尿道会师成功,定义为无需进一步的泌尿外科干预。次要结局包括内镜干预和/或尿道成形术的需求、尿道成形术的时间、尿道成形术的成功率以及长期功能结局。

结果

共有27例患者接受了一期尿道会师术,14例接受了耻骨上膀胱造瘘管置入术。平均随访时间为40个月(中位数24个月,范围1至152个月)。10例患者(37%)一期尿道会师成功,平均随访时间为67.3周(中位数27.3周,范围4至284周)。在17例(63%)失败的病例中,平均失败时间为9.7周(中位数8.5周,范围1至26周)。接受尿道会师术的7例患者(26%)和接受耻骨上膀胱造瘘管置入术的11例患者(79%)接受了尿道成形术。耻骨上膀胱造瘘管组尿道成形术的平均±标准差时间显著更短(14.6±7.6个月对5.8±1.6个月,p = 0.003)。手术时间、并发症、成功率或功能结局方面无差异。

结论

一期内镜下尿道会师术治疗创伤性尿道断裂伤在超过三分之一的治疗患者中可作为确定性治疗方法。在超过一半的失败病例中可避免进行正式的尿道成形术。

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