动态进化：巨型锚蛋白被唤醒。
Evolution in action: giant ankyrins awake.
机构信息
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA; Howard Hughes Medical Institute, Durham, NC 27710, USA.
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
出版信息
Dev Cell. 2015 Apr 6;33(1):1-2. doi: 10.1016/j.devcel.2015.03.017.
Reporting in Developmental Cell, Stephan et al. (2015) demonstrate critical axonal and presynaptic functions from acquisition of an enormous exon by the Drosophila ank2 gene. They propose that highly elongated ank2-XL molecules, associated with the plasma membrane through spectrin and ank2-L, extend deep into the axoplasm to promote microtubule organization.
在《发育细胞》杂志上，Stephan 等人（2015 年）的报告表明，果蝇 ank2 基因通过获取一个巨大的外显子，发挥了关键的轴突和突触前功能。他们提出，与质膜通过 spectrin 和 ank2-L 相关的高度延伸的 ank2-XL 分子，深入轴浆延伸，以促进微管组织。
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