Rector W G
Department of Medicine, Denver General Hospital, Colorado 80204-4507.
J Gen Intern Med. 1989 Nov-Dec;4(6):512-3. doi: 10.1007/BF02599550.
Pica, particularly ice-eating (pagophagia), is a recognized symptom of iron deficiency. The value of pica as a clue to the etiology of blood loss has never been studied.
Fifty-five unselected patients with iron-deficiency anemia due to gastrointestinal blood loss evaluated by a gastroenterology referral service at a city hospital.
The patients' mean hematocrit was 26 +/- 15% (SD). Thirty two (58%) had pica, and in 28 (88%) it manifested as pagophagia. Pica was present significantly more often in women (19/32, 68%) than in men (9/23, 39%, p less than 0.05). Pica occurred less frequently in patients with malignancy (2/9 vs. 30/46), but this difference was not significant.
Pica, a frequent symptom in patients with iron-deficiency anemia due to gastrointestinal blood loss, particularly women, is not of value in predicting the cause of bleeding.
异食癖，尤其是食冰癖，是缺铁的一种公认症状。异食癖作为失血病因线索的价值从未被研究过。
由一家城市医院的胃肠病转诊服务评估的55例因胃肠道失血导致缺铁性贫血的未经过挑选的患者。
患者的平均血细胞比容为26±15%（标准差）。32例（58%）有异食癖，其中28例（88%）表现为食冰癖。女性（19/32，68%）出现异食癖的频率显著高于男性（9/23，39%，p<0.05）。恶性肿瘤患者中异食癖的发生率较低（2/9对比30/46），但这种差异不显著。
异食癖是因胃肠道失血导致缺铁性贫血患者（尤其是女性）的常见症状，对预测出血原因没有价值。
