Rozenblat J, Magdassi S, Garti N
Casali Institute of Applied Chemistry, School of Applied Science and Technology, Hebrew University of Jerusalem, Israel.
J Microencapsul. 1989 Oct-Dec;6(4):515-26. doi: 10.3109/02652048909031171.
The objectives of the present study were to investigate the parameters affecting simple coacervation and the ability to encapsulate oleic acid using this technique. Coacervation has been achieved using different types of gelatin (bloom number, charge) and various electrolytes. The electrolytes used for the coacervation can be divided into three groups: (1) inert salts; (2) phase separation inducers, (a) precipitation inducing agents (PIA), and (b) coacervation inducing agents (CIA); (3) coacervation inhibiting agents. The encapsulation of oleic acid was evaluated with two types of gelatin and various emulsifiers (anionic, cationic and nonionic). For positively charged gelatin, it was found that the encapsulation is incomplete in presence of cationic emulsifiers. For negatively charged gelatin no general trend was observed. The stirring rate for each step of the preparation of the microcapsules was evaluated. It was found that high stirring is essential only in the cooling stage. The study was carried out in view of encapsulation of particular bacteria dispersed in the oil phase.
本研究的目的是调查影响简单凝聚的参数以及使用该技术封装油酸的能力。已使用不同类型的明胶（勃氏硬度值、电荷）和各种电解质实现了凝聚。用于凝聚的电解质可分为三组：（1）惰性盐；（2）相分离诱导剂，（a）沉淀诱导剂（PIA），和（b）凝聚诱导剂（CIA）；（3）凝聚抑制剂。用两种类型的明胶和各种乳化剂（阴离子型、阳离子型和非离子型）评估了油酸的封装情况。对于带正电荷的明胶，发现在阳离子型乳化剂存在下封装不完全。对于带负电荷的明胶，未观察到一般趋势。评估了微胶囊制备各步骤的搅拌速率。发现仅在冷却阶段高搅拌是必不可少的。鉴于封装分散在油相中的特定细菌开展了本研究。
