Thomson Jennifer M, Doruk Deniz, Mascio Bryan, Fregni Felipe, Cerruti Carlo
Harvard Graduate School of Education Cambridge, MA, USA.
Spaulding Neuromodulation Center, Spaulding Rehabilitation Hospital, Harvard Medical School Boston, MA, USA.
Front Hum Neurosci. 2015 Mar 16;9:114. doi: 10.3389/fnhum.2015.00114. eCollection 2015.
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that offers promise as an investigative method for understanding complex cognitive operations such as reading. This study explores the ability of a single session of tDCS to modulate reading efficiency and phonological processing performance within a group of healthy adults. Half the group received anodal or cathodal stimulation, on two separate days, of the left temporo-parietal junction while the other half received anodal or cathodal stimulation of the right homologue area. Pre- and post-stimulation assessment of reading efficiency and phonological processing was carried out. A larger pre-post difference in reading efficiency was found for participants who received right anodal stimulation compared to participants who received left anodal stimulation. Further, there was a significant post-stimulation increase in phonological processing speed following right hemisphere anodal stimulation. Implications for models of reading and reading impairment are discussed.
经颅直流电刺激(tDCS)是一种神经调节技术,有望成为理解诸如阅读等复杂认知操作的研究方法。本研究探讨了单次tDCS调节一组健康成年人阅读效率和语音处理能力的作用。一半参与者在两个不同日期接受左侧颞顶联合区的阳极或阴极刺激,另一半则接受右侧对应区域的阳极或阴极刺激。对阅读效率和语音处理进行刺激前和刺激后的评估。与接受左侧阳极刺激的参与者相比,接受右侧阳极刺激的参与者在阅读效率上的刺激前后差异更大。此外,右侧半球阳极刺激后语音处理速度有显著提高。还讨论了该研究对阅读和阅读障碍模型的意义。