Yılmaz Damla, Çapan Nermin, Canbakan Sema, Besler Halit Tanju
Faculty of Health Sciences, Department of Nutrition and Dietetics, Hacettepe University, Ankara, Turkey.
Department of Respiratory Medicine, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey.
Nutr J. 2015 Apr 10;14:35. doi: 10.1186/s12937-015-0020-5.
Fat-free mass (FFM) depletion has been shown to be a better predictor of mortality than BMI in chronic obstructive pulmonary disease (COPD) patients. The specific aim of the current study was to assess the nutritional status of stable COPD patients in relation to fat free mass index profiles.
We investigated 65 male moderate-to-severe stable COPD patients. A self-reported questionnaire was applied about general characteristics and smoking history. Nutritional intake was assessed by using a 54-item quantitative food frequency questionnaire. Weight, height, mid-upper arm circumference (MUAC), waist circumference (WC), handgrip strength and body composition measurements were taken by a trained dietitian. The data were analyzed with SPSS 15.0 software.
The mean age of the patients was 62.1 ± 8.9 years. Among all of the patients 13.8% was underweight (BMI < 21 kg/m(2)) and 18.5% had a low fat-free mass index (FFMI < 16 kg/m(2)). The percentages of the patients who did not meet the daily recommended intakes (RNI) were highest for magnesium (93.8%) and calcium (92.3%). Mean daily consumptions of milk-yogurt, red meat and fruits were significantly low in the low FFMI group compared to normal FFMI group (for all; p < 0.05). Patients with normal FFMI had significantly higher weight, height, WC, MUAC, handgrip strength, fat and fat-free mass than the patients with low FFMI (for all; p < 0.05).
Dieticians should be aware of COPD patients with low FFMI in order to evaluate the nutritional intake and therefore plan nutritional strategies to improve prognosis of the disease.
在慢性阻塞性肺疾病（COPD）患者中，无脂肪组织（FFM）消耗已被证明是比体重指数（BMI）更好的死亡率预测指标。本研究的具体目的是评估稳定期COPD患者与无脂肪质量指数谱相关的营养状况。
我们调查了65名男性中重度稳定期COPD患者。应用一份关于一般特征和吸烟史的自填问卷。通过使用一份包含54个条目的定量食物频率问卷评估营养摄入量。由一名经过培训的营养师测量体重、身高、上臂中部周长（MUAC）、腰围（WC）、握力和身体成分。数据用SPSS 15.0软件进行分析。
患者的平均年龄为62.1±8.9岁。在所有患者中，13.8%体重过轻（BMI＜21kg/m²），18.5%的无脂肪质量指数（FFMI）较低（FFMI＜16kg/m²）。未达到每日推荐摄入量（RNI）的患者百分比，镁最高（93.8%），钙次之（92.3%）。与正常FFMI组相比，低FFMI组的牛奶-酸奶、红肉和水果的平均每日消耗量显著较低（所有比较；p＜0.05）。FFMI正常的患者比FFMI低的患者体重、身高、WC、MUAC、握力、脂肪和无脂肪质量显著更高（所有比较；p＜0.05）。
营养师应关注FFMI较低的COPD患者，以便评估营养摄入情况，从而制定营养策略以改善疾病预后。
