Kurita Geana Paula, Sjøgren Per
Multidisciplinary Pain Centre, Department of Neuroanaesthesiology, Rigshospitalet Copenhagen University Hospital , Copenhagen , Denmark.
Acta Oncol. 2015 May;54(5):629-34. doi: 10.3109/0284186X.2014.996662. Epub 2015 Apr 9.
The number of patients surviving cancer disease has increased in last decades. Consequently, an emerging population with different needs due to long-term or late effects of cancer disease and/or treatment, e.g. chronic pain, is of major concern.
Chronic pain is one of the main problems in this population and prevalence varies between 16% and 50%. Most information derives from breast cancer patients assessed by surveys from national or local institutional databases. A Danish population-based survey estimated that 41.5% of all cancer survivors reported chronic pain. PAIN ETIOLOGY: Neuropathic pain seems to be the major pain etiology in cancer survivors and therefore adjuvant analgesics should be the first choice of analgesic treatment.
This article addresses the central aspects of pain epidemiology, mechanisms and the frequent pain syndromes met in cancer survivors. Pain management strategies are discussed according to the biopsychosocial model and with the rapidly growing number of cancer survivors the establishment of multidisciplinary clinics as a part of comprehensive cancer centers are proposed.
在过去几十年中,癌症疾病存活患者的数量有所增加。因此,由于癌症疾病和/或治疗的长期或晚期影响而产生不同需求的新兴人群,例如慢性疼痛患者,受到了主要关注。
慢性疼痛是这一人群的主要问题之一,患病率在16%至50%之间。大多数信息来自通过国家或地方机构数据库调查评估的乳腺癌患者。一项基于丹麦人群的调查估计,所有癌症幸存者中有41.5%报告有慢性疼痛。疼痛病因:神经病理性疼痛似乎是癌症幸存者的主要疼痛病因,因此辅助镇痛药应作为镇痛治疗的首选。
本文探讨了癌症幸存者疼痛流行病学、机制以及常见疼痛综合征的核心方面。根据生物心理社会模型讨论了疼痛管理策略,并随着癌症幸存者数量的迅速增加,提议在综合癌症中心设立多学科诊所。